Spyre Therapeutics, Inc.

Fundamentals7.5
Price Action6.5
News Sentiment8.0
AI Rating
7.2

Key Drivers

  • Strong Liquidity
  • No Revenue
  • Rich Valuation

AI
AI Summary

7.2

SYRE has shifted from a survival-funding story to a high-upside, high-valuation clinical execution bet: with $1.2B cash and positive SKYLINE UC data, the stock now hinges on replicating efficacy across the 2026 readout calendar, where any miss could sharply reset sentiment after the recent rerating.

ClinicalCatalyst
ExecutionRisk
Biotech‍

Price Chart

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Financial Metrics

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Revenue (TTM)
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Net Income (TTM)
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EPS (Q)
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MCAP

Deep Analysis

Research tool. Not personalized advice.

Fundamental Analysis

7.5

Key Financial Insights:

  • Strong Liquidity
  • No Revenue
  • Rich Valuation

SYRE has excellent liquidity and no debt, but persistent no-revenue cash burn, widening quarterly losses, and a 9.19x price-to-book make the stock look financially safe near term yet expensive and risky longer term.

Liquidity
CashBurn

Price Behavior

6.5
Research tool. Not personalized advice. Technical analysis is for informational purposes only.

Key Price Behavior Insights:

  • Rebound intact
  • Resistance cap
  • Momentum cooling

Over the last month, SYRE rebounded sharply from a late-April low near $68.63, but is now consolidating under $76.3-$76.4 resistance while holding above $73 support.

constructive
consolidation
Support Level: $73.00-$73.10
Resistance Level: $76.30-$76.40

Sharp rebound from $68.63 to the $76.31-$76.43 area, then a pullback into consolidation

Sentiment & News

8.0

Key News Insights:

  • Phase 2 momentum
  • Strong cash runway
  • Accelerated readouts

Spyre Therapeutics (SYRE) posted encouraging Phase 2 efficacy and safety data, accelerated multiple readouts, and boosted its balance sheet with a $463M raise, supporting a longer cash runway into 2029.

biotech
clinicaldata

The positive clinical signal plus ample funding and a packed catalyst calendar should remain supportive for SYRE's stock